miRNA description for let-7i
miRNA accession	let-7i
Species	Homo sapiens
let-7i identified in exosomes derived from the following tissue/cell type
Breast cancer cells [Exosomes]	20976003
Dendritic cells [Exosomes]	21505438
Lung cells [Microvesicles]	20079801
Plasma [Exosomes]	29295981
Plasma [Exosomes]	29295981
Plasma [Exosomes]	29295981
Plasma [Exosomes]	29295981
Plasma [Exosomes]	29295981
Plasma [Exosomes]	29295981
Plasma [Exosomes]	29295981
Plasma [Exosomes]	29295981
Serum [Exosomes]	18589210
Stomach cancer cells [Exosomes]	20949044
Stomach cancer cells [Exosomes]	20949044
T cells [Exosomes]	21505438
Experiment description of studies that identified let-7i in exosomes
1 Experiment ID 333 Identified molecule miRNA Identification method Microarray PubMed ID 20976003    Organism Homo sapiens Experiment description Selective release of microRNA species from normal and malignant mammary epithelial cells Authors Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM Journal name PLoS One Publication year 2010 Sample Breast cancer cells Sample name MCF-7 Molecules identified in the study Protein miRNA Methods used in the study Slot blot RT-PCR Microarray EV-TRACK -
2 Experiment ID 117 Identified molecule miRNA Identification method Human miRNA Microarray Kit PubMed ID 21505438    Organism Homo sapiens Experiment description Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Authors Mittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F. Journal name NATCOM Publication year 2011 Sample Dendritic cells Sample name Dendritic cells Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Microarray EV-TRACK EV110049: EV-METRIC:11%
3 Experiment ID 324 Identified molecule miRNA Identification method Microarray or RT-PCR PubMed ID 20079801    Organism Mus musculus Experiment description Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription Authors Aliotta JM, Pereira M, Johnson KW, de Paz N, Dooner MS, Puente N, Ayala C, Brilliant K, Berz D, Lee D, Ramratnam B, McMillan PN, Hixson DC, Josic D, Quesenberry PJ Journal name Exp Hematol Publication year 2010 Sample Lung cells Sample name Lung cells Molecules identified in the study Protein miRNA Methods used in the study FACS RT-PCR EV-TRACK EV100071: EV-METRIC:14%
4 Experiment ID 2276 Identified molecule miRNA Identification method RT-qPCR PubMed ID 29295981    Organism Homo sapiens Experiment description Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Authors Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T. Journal name Nat Commun Publication year 2018 Sample Plasma Sample name Healthy controls Molecules identified in the study Protein miRNA Methods used in the study Western blotting Microarray RT-qPCR EV-TRACK -
5 Experiment ID 2277 Identified molecule miRNA Identification method RT-qPCR PubMed ID 29295981    Organism Homo sapiens Experiment description Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Authors Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T. Journal name Nat Commun Publication year 2018 Sample Plasma Sample name Multiple sclerosis Molecules identified in the study miRNA Methods used in the study Microarray RT-qPCR EV-TRACK -
6 Experiment ID 2278 Identified molecule miRNA Identification method RT-qPCR PubMed ID 29295981    Organism Homo sapiens Experiment description Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Authors Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T. Journal name Nat Commun Publication year 2018 Sample Plasma Sample name Relapsing-remitting multiple sclerosis Molecules identified in the study miRNA Methods used in the study RT-qPCR EV-TRACK -
7 Experiment ID 2279 Identified molecule miRNA Identification method RT-qPCR PubMed ID 29295981    Organism Homo sapiens Experiment description Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Authors Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T. Journal name Nat Commun Publication year 2018 Sample Plasma Sample name Secondary-progressive multiple sclerosis Molecules identified in the study miRNA Methods used in the study RT-qPCR EV-TRACK -
8 Experiment ID 2280 Identified molecule miRNA Identification method RT-qPCR PubMed ID 29295981    Organism Homo sapiens Experiment description Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Authors Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T. Journal name Nat Commun Publication year 2018 Sample Plasma Sample name Multiple sclerosis in remission phase Molecules identified in the study miRNA Methods used in the study RT-qPCR EV-TRACK -
9 Experiment ID 2281 Identified molecule miRNA Identification method RT-qPCR PubMed ID 29295981    Organism Homo sapiens Experiment description Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Authors Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T. Journal name Nat Commun Publication year 2018 Sample Plasma Sample name Multiple sclerosis in relapse phase Molecules identified in the study miRNA Methods used in the study RT-qPCR EV-TRACK -
10 Experiment ID 2282 Identified molecule miRNA Identification method RT-qPCR PubMed ID 29295981    Organism Homo sapiens Experiment description Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Authors Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T. Journal name Nat Commun Publication year 2018 Sample Plasma Sample name Male with multiple sclerosis Molecules identified in the study miRNA Methods used in the study RT-qPCR EV-TRACK -
11 Experiment ID 2283 Identified molecule miRNA Identification method RT-qPCR PubMed ID 29295981    Organism Homo sapiens Experiment description Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Authors Kimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T. Journal name Nat Commun Publication year 2018 Sample Plasma Sample name Female with multiple sclerosis Molecules identified in the study miRNA Methods used in the study RT-qPCR EV-TRACK -
12 Experiment ID 45 Identified molecule miRNA Identification method 467microRNA Array PubMed ID 18589210    Organism Homo sapiens Experiment description MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Authors Taylor DD, Gercel-Taylor C Journal name GO Publication year 2008 Sample Serum Sample name Serum - Papillary adenocarcinoma of ovary Molecules identified in the study Protein miRNA Methods used in the study Western blotting MicroRNA array EV-TRACK -
13 Experiment ID 88 Identified molecule miRNA Identification method Human miRNA Microarray Kit RT-PCR PubMed ID 20949044    Organism Homo sapiens Experiment description Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Authors Ohshima K, Inoue K, Fujiwara A, Hatakeyama K, Kanto K, Watanabe Y, Muramatsu K, Fukuda Y, Ogura S, Yamaguchi K, Mochizuki T. Journal name PLOS1 Publication year 2010 Sample Stomach cancer cells Sample name AZ-P7a Molecules identified in the study Protein miRNA Methods used in the study Immunoelectron microscopy Western blotting RT-PCR Human miRNA Microarray Kit EV-TRACK EV100005: EV-METRIC:44%
14 Experiment ID 82 Identified molecule miRNA Identification method RT-PCR PubMed ID 20949044    Organism Homo sapiens Experiment description Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Authors Ohshima K, Inoue K, Fujiwara A, Hatakeyama K, Kanto K, Watanabe Y, Muramatsu K, Fukuda Y, Ogura S, Yamaguchi K, Mochizuki T. Journal name PLOS1 Publication year 2010 Sample Stomach cancer cells Sample name AZ-521 Molecules identified in the study Protein miRNA Methods used in the study Western blotting RT-PCR Human miRNA Microarray Kit EV-TRACK EV100005: EV-METRIC:44%
15 Experiment ID 115 Identified molecule miRNA Identification method Human miRNA Microarray Kit PubMed ID 21505438    Organism Homo sapiens Experiment description Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Authors Mittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F. Journal name NATCOM Publication year 2011 Sample T cells Sample name J77 Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Microarray EV-TRACK EV110049: EV-METRIC:11%